Reaction: 3,5,7-trioxododecanoyl-CoA = CoA + 2,4-dihydroxy-6-pentylbenzoate
For diagram of reaction click here.
Glossary: 2,4-dihydroxy-6-pentylbenzoate = olivetolate
Other name(s): OAC
Systematic name: 3,5,7-trioxododecanoyl-CoA CoA-lyase (olivetolate-forming)
Comments: Part of the cannabinoids biosynthetic pathway in the plant Cannabis sativa.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:
References:
1. Gagne, S.J., Stout, J.M., Liu, E., Boubakir, Z., Clark, S.M. and Page, J.E. Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides. Proc. Natl. Acad. Sci. USA 109 (2012) 12811-12816. [PMID: 22802619]