Reaction: all-trans-hexaprenyl diphosphate = talaropentaene + diphosphate
For diagram of reaction click here
Glossary: talaropentaene = (3aS,5E,9E)-3a,6,10-trimethyl-1-[(2ξ,4E,8E)-undeca-5,9-dien-2-yl]-3,3a,4,7,8,11,12-octahydrocyclopenta[11]annulene
Other name(s): TvTS
Systematic name: pentaprenyl-diphosphate diphosphate-lyase [cyclizing, talaropentaene-forming]
Comments: Isolated from the fungus Talaromyces verruculosus.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Tao, H., Lauterbach, L., Bian, G., Chen, R., Hou, A., Mori, T., Cheng, S., Hu, B., Lu, L., Mu, X., Li, M., Adachi, N., Kawasaki, M., Moriya, T., Senda, T., Wang, X., Deng, Z., Abe, I., Dickschat, J.S. and Liu, T. Discovery of non-squalene triterpenes. Nature 606 (2022) 414-419. [PMID: 35650436]