Reaction: geranylfarnesyl diphosphate = somaliensene A + diphosphate
For diagram of reaction click here
Glossary: somaliensene A = (1S,5R,6R)-6-methyl-6-[(3E,7E,11E)-trimethyltrideca-3,7,11-trien-1-yl]bicyclo[3.1.1]hept-2-ene
Other name(s): stsC (gene name)
Systematic name: geranylfarnesyl-diphosphate diphosphate-lyase (cyclizing, somaliensene A-forming)
Comments: A sesterterpenoid synthase enzyme isolated from the bacterium Streptomyces somaliensis. The enzyme also produces somalensene B (cf. EC 4.2.3.217, somaliensene B synthase).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Yang, Y., Zhang, Y., Zhang, S., Chen, Q., Ma, K., Bao, L., Tao, Y., Yin, W., Wang, G. and Liu, H. Identification and characterization of a membrane-bound sesterterpene cyclase from Streptomyces somaliensis. J Nat Prod 81 (2018) 1089-1092. [PMID: 29553734]