IUBMB Enzyme Nomenclature

EC 4.2.3.181

Accepted name: selina-4(15),7(11)-diene synthase

Reaction: (2E,6E)-farnesyl diphosphate = selina-4(15),7(11)-diene + diphosphate

For diagram of reaction click here

Other name(s): SdS

Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, selina-4(15),7(11)-diene-forming)

Comments: Isolated from the bacteria Streptomyces pristinaespiralis and S. somaliensis.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Rabe, P. and Dickschat, J.S. Rapid chemical characterization of bacterial terpene synthases. Angew. Chem. Int. Ed. Engl. 52 (2013) 1810-1812. [PMID: 23307484]

2. Baer, P., Rabe, P., Fischer, K., Citron, C.A., Klapschinski, T.A., Groll, M. and Dickschat, J.S. Induced-fit mechanism in class I terpene cyclases. Angew. Chem. Int. Ed. Engl. 53 (2014) 7652-7656. [PMID: 24890698]

[EC 4.2.3.181 created 2017]


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