IUBMB Enzyme Nomenclature

EC 4.2.3.175

Accepted name: 10-epi-cubebol synthase

Reaction: (2E,6E)-farnesyl diphosphate + H2O = 10-epi-cubebol + diphosphate

For diagram of reaction click here

Other name(s): sce6369

Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, 10-epi-cubebol-forming)

Comments: Isolated from the bacterium Sorangium cellulosum So ce56. The enzyme is also responsible for the formation of trace amounts of many other sesquiterpenes, mainly cadinanes and cubebanes.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Schifrin, A., Khatri, Y., Kirsch, P., Thiel, V., Schulz, S. and Bernhardt, R. A single terpene synthase is responsible for a wide variety of sesquiterpenes in Sorangium cellulosum Soce56. Org. Biomol. Chem. 14 (2016) 3385-3393. [PMID: 26947062]

[EC 4.2.3.175 created 2017]


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