Reaction: geranyl diphosphate + H2O = (–)-α-terpineol + diphosphate
For diagram of reaction click here.
Systematic name: geranyl-diphosphate diphosphate-lyase [cyclizing, (–)-α-terpineol-forming]
Comments: The enzyme has been characterized from Vitis vinifera (grape). Also forms some 1,8-cineole and traces of other monoterpenoids.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:
References:
1. Martin, D.M. and Bohlmann, J. Identification of Vitis vinifera (–)-α-terpineol synthase by in silico screening of full-length cDNA ESTs and functional characterization of recombinant terpene synthase. Phytochemistry 65 (2004) 1223-1229. [PMID: 15184006]
2. Lucker, J., Bowen, P. and Bohlmann, J. Vitis vinifera terpenoid cyclases: functional identification of two sesquiterpene synthase cDNAs encoding (+)-valencene synthase and (–)-germacrene D synthase and expression of mono- and sesquiterpene synthases in grapevine flowers and berries. Phytochemistry 65 (2004) 2649-2659. [PMID: 15464152]