IUBMB Enzyme Nomenclature

EC 4.2.1.57

Accepted name: isohexenylglutaconyl-CoA hydratase

Reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O

Other name(s): 3-hydroxy-3-isohexenylglutaryl-CoA-hydrolase; isohexenylglutaconyl coenzyme A hydratase; β-isohexenylglutaconyl-CoA-hydratase; 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase

Systematic name: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase [3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA-forming]

Comments: Also acts on dimethylacryloyl-CoA and farnesoyl-CoA.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 37290-84-9

References:

1. Seubert, W. and Fass, E. Untersuchungen über den bakterielle Abbau von Isoprenoiden. IV. Reinigung und Eigenschaftender β-Isohexenylglutaconyl-CoA-hydratase und β-Hydroxy-β-isohexenylglutaryl-CoA-lyase. Biochem. Z. 341 (1964) 23-34.

[EC 4.2.1.57 created 1972]


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