Reaction: peregrinol diphosphate = geranylgeranyl diphosphate + H2O
For diagram of reaction click here
Glossary: peregrinol diphosphate = (13E)-9-hydroxy-8α-labda-13-en-15-yl diphosphate
Other name(s): MvCPS1
Systematic name: geranylgeranyl-diphosphate hydro-lyase (peregrinol diphosphate forming)
Comments: Isolated from the plant Marrubium vulgare (white horehound). Involved in marrubiin biosynthesis.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
1. Zerbe, P., Chiang, A., Dullat, H., O'Neil-Johnson, M., Starks, C., Hamberger, B. and Bohlmann, J. Diterpene synthases of the biosynthetic system of medicinally active diterpenoids in Marrubium vulgare. Plant J. 79 (2014) 914-927. [PMID: 24990389]