IUBMB Enzyme Nomenclature

EC 4.2.1.156

Accepted name: L-talarate dehydratase

Reaction: L-altarate = 5-dehydro-4-deoxy-D-glucarate + H2O

Glossary: L-altrarate = L-talarate = (2R,3R,4S,5R)-2,3,4,5-tetrahydroxyhexanedioate

Other name(s): L-talarate hydro-lyase

Systematic name: L-altarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)

Comments: Requires Mg2+. The enzyme, isolated from the bacteria Salmonella typhimurium and Polaromonas sp. JS666, also has activity with galactarate (cf. EC 4.2.1.42, galactarate dehydratase).

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Yew, W.S., Fedorov, A.A., Fedorov, E.V., Almo, S.C. and Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2. Biochemistry 46 (2007) 9564-9577. [PMID: 17649980]

[EC 4.2.1.156 created 2015]


Return to EC 4.2.1 home page
Return to EC 4.2 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page