IUBMB Enzyme Nomenclature

EC 4.2.1.127

Accepted name: linalool dehydratase

Reaction: (3S)-linalool = myrcene + H2O

For diagram of reaction click here.

Glossary: linalool = 3,7-dimethylocta-1,6-dien-3-ol

Other name(s): linalool hydro-lyase (myrcene-forming)

Systematic name: (3S)-linalool hydro-lyase (myrcene-forming)

Comments: In absence of oxygen the bifunctional linalool dehydratase-isomerase can catalyse in vitro two reactions, the hydration of myrcene to (3S)-linalool and the isomerization of (3S)-linalool to geraniol, the latter activity being classified as EC 5.4.4.4, geraniol isomerase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Brodkorb, D., Gottschall, M., Marmulla, R., Lüddeke, F. and Harder, J. Linalool dehydratase-isomerase, a bifunctional enzyme in the anaerobic degradation of monoterpenes. J. Biol. Chem. 285 (2010) 30436-30442. [PMID: 20663876]

2. Lüddeke, F. and Harder, J. Enantiospecific (S)-(+)-linalool formation from β-myrcene by linalool dehydratase-isomerase. Z. Naturforsch. C 66 (2011) 409–412. [PMID: 21950166]

[EC 4.2.1.127 created 2011]


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