Reaction: 2-dehydro-3-deoxy-L-fuconate = pyruvate + (S)-lactaldehyde
Other name(s): 2-keto-3-deoxy-L-fuconate aldolase; L-2-keto-3-deoxyfuconate aldolase; fucH (gene name)
Systematic name: 2-dehydro-3-deoxy-L-fuconate (S)-lactaldehyde-lyase (pyruvate-forming)
Comments: The enzyme, characterized from the bacteria Veillonella ratti and Campylobacter jejuni, participates in an L-fucose degradation pathway. It also has significant activity with 2-dehydro-3-deoxy-D-pentonate (cf. EC 4.1.2.28, 2-dehydro-3-deoxy-D-pentonate aldolase).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Watanabe, S. Characterization of L-2-keto-3-deoxyfuconate aldolases in a nonphosphorylating L-fucose metabolism pathway in anaerobic bacteria. J. Biol. Chem. 295 (2020) 1338-1349. [PMID: 31914410]