IUBMB Enzyme Nomenclature

EC 4.1.1.4

EC 4.1.1.4

Accepted name: acetoacetate decarboxylase

Reaction: acetoacetate + H+ = acetone + CO2

For diagram click here.

Other name(s): acetoacetic acid decarboxylase; acetoacetate carboxy-lyase

Systematic name: acetoacetate carboxy-lyase (acetone-forming)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9025-03-0

References:

1. Davies, R. Studies of the acetone-butanol fermentation. 4. Acetoacetic acid decarboxylase of Cl. acetobutylicum (BY). Biochem. J. 37 (1943) 230-238.

2. Zerner, B., Coutts, S.M., Lederer, F., Waters, H.H. and Westheimer, F.H. Acetoacetate decarboxylase. Preparation of the enzyme. Biochemistry 5 (1966) 813-816. [PMID: 5911291]

3. Ho, M.C., Menetret, J.F., Tsuruta, H. and Allen, K.N. The origin of the electrostatic perturbation in acetoacetate decarboxylase. Nature 459 (2009) 393-397. [PMID: 19458715]

[EC 4.1.1.4 created 1961]


Return to EC 4.1.1 home page
Return to EC 4.3 home page
Return to EC 4 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page