IUBMB Enzyme Nomenclature

EC 4.1.1.18

Accepted name: lysine decarboxylase

Reaction: L-lysine = cadaverine + CO2

Other name(s): L-lysine carboxy-lyase

Systematic name: L-lysine carboxy-lyase (cadaverine-forming)

Comments: A pyridoxal-phosphate protein. Also acts on 5-hydroxy-L-lysine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9024-76-4

References:

1. Gale, E.F. and Epps, H.M.R. Studies on bacterial amino-acid decarboxylases. 1. l(+)-lysine decarboxylase. Biochem. J. 38 (1944) 232-242.

2. Soda, K. and Moriguchi, M. Crystalline lysine decarboxylase. Biochem. Biophys. Res. Commun. 34 (1969) 34-39. [PMID: 5762458]

[EC 4.1.1.18 created 1961]


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