IUBMB Enzyme Nomenclature

EC 4.1.1.118

Accepted name: isophthalyl-CoA decarboxylase

Reaction: isophthalyl-CoA = benzoyl-CoA + CO2

Other name(s): IPCD

Systematic name: isophthalyl-CoA carboxy-lyase

Comments: The enzyme, characterized from the bacterium Syntrophorhabdus aromaticivorans, participates in an anaerobic isophthalate degradation pathway. The enzyme requires a prenylated flavin mononucleotide cofactor.

References:

1. Junghare, M., Spiteller, D. and Schink, B. Anaerobic degradation of xenobiotic isophthalate by the fermenting bacterium Syntrophorhabdus aromaticivorans. ISME J. 13 (2019) 1252-1268. [PMID: 30647456]

[EC 4.1.1.118 created 2019]


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