IUBMB Enzyme Nomenclature


Accepted name: Cl--transporting ATPase

Reaction: ATP + H2O + Cl-out = ADP + phosphate + Cl-in

Other name(s): Cl--translocating ATPase; Cl--motive ATPase

Systematic name: ATP phosphohydrolase (Cl--importing)

Comments: A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. An animal and plant enzyme involved in the import of chloride anions.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Ohhashi, T., Katsu, T. and Ikeda, M. Improvement of reconstitution of the Cl--translocating ATPase isolated from Acetabularia acetabulum into liposomes and several anion pump characteristics. Biochim. Biophys. Acta 1106 (1992) 165-170. [PMID: 1533790]

2. Gerencser, G.A. and Purushotham, K.R. Reconstituted Cl- pump protein: a novel Cl--motive ATPase. J. Bioenerget. Biomembr. 28 (1996) 459-469. [PMID: 8953378]

3. Inagaki, C., Hara, M. and Zeng, X.T. A Cl- pump in rat brain neurons. J. Exp. Zool. 275 (1996) 262-268. [PMID: 8759922]

[EC created 2000]

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