Reaction: dTTP + H2O = dTDP + phosphate
Other name(s): thymidine triphosphate nucleotidohydrolase; dTTPase; deoxythymidine-5'-triphosphatase
Systematic name: dTTP nucleotidohydrolase
Comments: Also acts, more slowly, on dUTP and UTP.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37367-74-1
References:
1. Dahlmann, N. Human serum thymidine triphosphate nucleotidohydrolase: purification and properties of a new enzyme. Biochemistry 21 (1982) 6634-6639. [PMID: 6297538]