IUBMB Enzyme Nomenclature

EC 3.5.4.23

Accepted name: blasticidin-S deaminase

Reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3

Systematic name: blasticidin-S aminohydrolase

Comments: Catalyses the deamination of the cytosine moiety of the antibiotics blasticidin S, cytomycin and acetylblasticidin S.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 54576-55-5

References:

1. Yamaguchi, I., Shibata, H., Seto, H. and Misato, T. Isolation and purification of blasticidin S deaminase from Aspergillus terreus. J. Antibiot. 28 (1975) 7-14. [PMID: 236272]

[EC 3.5.4.23 created 1976]


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