Reaction: cytosine + H2O = uracil + NH3
Other name(s): isocytosine deaminase
Systematic name: cytosine aminohydrolase
Comments: Also acts on 5-methylcytosine.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9025-05-2
References:
1. Cohen, S.S. and Barner, H.D. The conversion of 5-methyldeoxycytidine to thymidine in vitro and in vivo. J. Biol. Chem. 226 (1957) 631-642.
2. Kream, J. and Chargaff, E. On the cytosine deaminase of yeast. J. Am. Chem. Soc. 74 (1952) 5157-5160.