IUBMB Enzyme Nomenclature

EC 3.4.24.37

Accepted name: saccharolysin

Reaction: Cleavage of ProPhe and AlaAla bonds

Other names: proteinase yscD; yeast cysteine proteinase D (Misleading); Saccharomyces cerevisiae proteinase yscD

Comments: An 83 kDa cytoplasmic thiol-dependent metalloendopeptidase from Saccharomyces cerevisiae. In peptidase family M3 (thimet oligopeptidase family). Formerly EC 3.4.22.22

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, CAS registry number: 96779-48-5

References:

1. Achstetter, T., Ehmann, C. and Wolf, D.H. Proteinase yscD. Purification and characterization of a new yeast peptidase. J. Biol. Chem. 260 (1985) 4584-4590. [PMID: 3886641]

2. Garcia-Alvarez, N., Teichert, U. and Wolf, D.H. Proteinase yscD mutants of yeast. Isolation and characterization. Eur. J. Biochem. 163 (1987) 339-346. [PMID: 3545833]

[EC 3.4.24.37 created 1989 as EC 3.4.22.22, transferred 1992 to EC 3.4.24.37]


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