> Arg; higher selectivity than trypsin. Converts fibrin into soluble products
Reaction: Preferential cleavage: Lys > Arg; higher selectivity than trypsin. Converts fibrin into soluble products
Other names: fibrinase; fibrinolysin; actase; serum tryptase; thrombolysin
Comments: Formed from plasminogen by proteolysis which results in multiple forms of the active plasmin. In peptidase family S1 (trypsin family). Formerly EC 3.4.4.14
Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, PDB, CAS registry number: 9001-90-5
References
1. Castellino, F.J. and Sodetz, J.M. Rabbit plasminogen and plasmin isozymes. Methods Enzymol. 45 (1976) 273-286. [PMID: 138065]
2. Castellino, F.J. and Powell, J.R. Human plasminogen. Methods Enzymol. 80 (1981) 365-378. [PMID: 6210827]
3. Robbins, K.C., Summaria, L. and Wohl, R.C. Human plasmin. Methods Enzymol. 80 (1981) 379-387. [PMID: 6210828]