IUBMB Enzyme Nomenclature

EC 3.4.17.4

Accepted name: Gly-Xaa carboxypeptidase

Reaction: Release of a C-terminal amino acid from a peptide in which glycine is the penultimate amino acid, e.g. Z-GlyLeu

Other names: glycine carboxypeptidase; carboxypeptidase a; carboxypeptidase S; peptidase α; yeast carboxypeptidase; Gly-X carboxypeptidase

Comments: From yeast. In peptidase family M20 (glutamate carboxypeptidase family). Formerly EC 3.4.2.3, EC 3.4.12.8 and EC 3.4.17.9

Links to other databases: BRENDA, EXPASY, KEGG, GTD, MEROPS, Metacyc, CAS registry number: 9025-25-6

References

1. Félix, F. and Brouillet, N. Purification et proprietes de deux peptidases de levure de brasserie. Biochim. Biophys. Acta 122 (1966) 127-144. [PMID: 4961236]

2. Wolf, D.H. and Ehmann, C. Carboxypeptidase S from yeast: regulation of its activity during vegetative growth and differentiation. FEBS Lett. 91 (1978) 59-62. [PMID: 352726]

[EC 3.4.17.4 created 1961 as EC 3.4.2.3, transferred 1972 to EC 3.4.12.8, transferred 1978 to EC 3.4.17.4 (EC 3.4.17.9 created 1981, incorporated 1992)]


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