IUBMB Enzyme Nomenclature

EC 3.4.11.19

Accepted name: D-stereospecific aminopeptidase

Reaction: Release of an N-terminal D-amino acid from a peptide, XaaYaa-, in which Xaa is preferably D-Ala, D-Ser or D-Thr. D-Amino acid amides and methyl esters also are hydrolysed, as is glycine amide

Other name(s): D-aminopeptidase

Comments: Known from the bacterium Ochrobactrum anthropi. In peptidase family S12 (D-Ala-D-Ala carboxypeptidase family) [2]

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, PDB, CAS registry number: 57534-78-8

References

1. Asano, Y., Nakazawa, A., Kato, Y. and Kondo, K. Properties of a novel D-stereospecific aminopeptidase from Ochrobactrum anthropi. J. Biol. Chem. 264 (1989) 14233-14239. [PMID: 2760064]

2. Asano, Y., Kato, Y., Yamada, A. and Kondo, K. Structural similarity of D-aminopeptidase to carboxypeptidase DD and β-lactamases. Biochemistry 31 (1992) 2316-2328. [PMID: 1540587]

[EC 3.4.11.19 created 1993]


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