IUBMB Enzyme Nomenclature


Accepted name: bacterial leucyl aminopeptidase

Reaction: Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids

Other names: Aeromonas proteolytica aminopeptidase

Comments: A zinc enzyme. Forms of the enzyme have been isolated from Aeromonas proteolytica, Escherichia coli and Streptococcus thermophilus . Examples are known from peptidase families M17 and M28 (of leucyl aminopeptidase and aminopeptidase Y, respectively)

Links to other databases: BRENDA, EXPASY, KEGG, MEROPS, Metacyc, PDB, CAS registry number: 37288-67-8


1. Prescott, J.M. and Wilkes, S.H. Aeromonas aminopeptidase: purification and some general properties. Arch. Biochem. Biophys. 117 (1966) 328-336. [PMID: 4961737]

2. Dick, A.J., Matheson, A.T. and Wang, J.H. A ribosomal-bound aminopeptidase in Escherichia coli B: purification and properties. Can. J. Biochem. 48 (1970) 1181-1188. [PMID: 4920230]

3. Rabier, D. and Desmazeaud, M.J. Inventaire des différentes activités peptidasiques intracellulaires de Streptococcus thermophilus. Purification et propriétés d'une dipeptide-hydrolase et d'une aminopeptidase. Biochimie (Paris) 55 (1973) 389-404. [PMID: 4749719]

[EC created 1972]

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