IUBMB Enzyme Nomenclature

EC 3.2.2.17

Accepted name: deoxyribodipyrimidine endonucleosidase

Reaction: Cleaves the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue

Other name(s): pyrimidine dimer DNA-glycosylase; endonuclease V; deoxyribonucleate pyrimidine dimer glycosidase; pyrimidine dimer DNA glycosylase; T4-induced UV endonuclease; PD-DNA glycosylase

Systematic name: deoxy-D-ribocyclobutadipyrimidine polynucleotidodeoxyribohydrolase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 75302-33-9

References:

1. Haseltine, W.A., Gordon, L.K., Lindan, C.P., Grafstrom, R.H., Shaper, N.L. and Grossman, L. Cleavage of pyrimidine dimers in specific DNA sequences by a pyrimidine dimer DNA-glycosylase of M. luteus. Nature 285 (1980) 634-641. [PMID: 6248789]

[EC 3.2.2.17 created 1983]


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