IUBMB Enzyme Nomenclature

EC 3.2.2.15

Accepted name: DNA-deoxyinosine glycosylase

Reaction: Hydrolyses DNA and polynucleotides, releasing free hypoxanthine

Other name(s): DNA(hypoxanthine) glycohydrolase; deoxyribonucleic acid glycosylase; hypoxanthine-DNA glycosylase

Systematic name: DNA-deoxyinosine deoxyribohydrolase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 68247-62-1

References:

1. Karran, P. and Lindahl, T. Enzymatic excision of free hypoxanthine from polydeoxynucleotides and DNA containing deoxyinosine monophosphate residues. J. Biol. Chem. 253 (1978) 5877-5879. [PMID: 98523]

[EC 3.2.2.15 created 1980, modified 1982, modified 2000]


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