IUBMB Enzyme Nomenclature

EC 3.2.1.68

Accepted name: isoamylase

Reaction: Hydrolysis of (1→6)-α-D-glucosidic branch linkages in glycogen, amylopectin and their β-limit dextrins

Glossary entries:
pullulan = a linear polymer of 1→6-linked maltotriose units.

Other name(s): debranching enzyme

Systematic name: glycogen α-1,6-glucanohydrolase

Comments: Also readily hydrolyses amylopectin. Differs from EC 3.2.1.41 (pullulanase) and EC 3.2.1.142 (limit dextrinase) by its inability to hydrolyse pullulan, and by limited action on α-limit dextrins. Maltose is the smallest sugar it can release from an α-(1→6)-linkage.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9067-73-6

References:

1. Yokobayashi, K., Misaki, A. and Harada, T. Purification and properties of Pseudomonas isoamylase. Biochim. Biophys. Acta 212 (1970) 458-469. [PMID: 5456995]

[EC 3.2.1.68 created 1972, modified 1976, modified 2000]


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