Reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide
Other name(s): α-Kdo-ase
Systematic name: 3-deoxyoctulosonyl-lipopolysaccharide hydrolase
Comments: Releases Kdo (α- and β-linked 3-deoxy-D-manno-octulosonic acid) from different lipopolysaccharides, including Re-LPS from Escherichia coli and Salmonella, Rd-LPS from S. minnesota, and de-O-acyl-re-LPS. 4-Methylumbelliferyl-α-Kdo (α-Kdo-OMec) is also a substrate.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 199128-67-1
1. Li, Y.T., Wang, L.X., Pavlova, N.V., Li, S.C. and Lee, Y.C. α-KDOase activity in oyster and synthesis of α- and β-4-methylumbelliferyl ketosides of 3-deoxy-D-manno-octulosonic acid (KDO) J. Biol. Chem. 272 (1997) 26419-26424. [PMID: 9334217]