IUBMB Enzyme Nomenclature

EC 3.1.6.18

Accepted name: glucuronate-2-sulfatase

Reaction: Hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate

Other name(s): glucurono-2-sulfatase

Systematic name: polysaccharide-2-O-sulfo-D-glucuronate 2-sulfohydrolase

Comments: Does not act on iduronate 2-sulfate residues (cf. EC 3.1.6.13 iduronate-2-sulfatase)

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 98597-45-6

References:

1. Shaklee, P.N., Glaser, J.H. and Conrad, H.E. A sulfatase specific for glucuronic acid 2-sulfate residues in glycosaminoglycans. J. Biol. Chem. 260 (1985) 9146-9149. [PMID: 4019466]

[EC 3.1.6.18 created 1989]


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