Reaction: ADP-ribose 1"-phosphate + H2O = ADP-D-ribose + phosphate
Other name(s): POA1; Appr1p phosphatase; Poa1p; ADP-ribose 1"-phosphate phosphohydrolase
Systematic name: ADP-D-ribose 1"-phosphate phosphohydrolase
Comments: The enzyme is highly specific for ADP-ribose 1"-phosphate. Involved together with EC 22.214.171.124, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, in the breakdown of adenosine diphosphate ribose 1",2"-cyclic phosphate (Appr>p), a by-product of tRNA splicing.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:
1. Shull, N.P., Spinelli, S.L. and Phizicky, E.M. A highly specific phosphatase that acts on ADP-ribose 1"-phosphate, a metabolite of tRNA splicing in Saccharomyces cerevisiae. Nucleic Acids Res. 33 (2005) 650-660. [PMID: 15684411]