IUBMB Enzyme Nomenclature

EC 3.1.2.21

Accepted name: dodecanoyl-[acyl-carrier protein] hydrolase

Reaction: a dodecanoyl-[acyl-carrier protein] + H2O = an [acyl-carrier protein] + dodecanoate

Other name(s): lauryl-acyl-carrier-protein hydrolase; dodecanoyl-acyl-carrier-protein hydrolase; dodecyl-acyl-carrier protein hydrolase

Systematic name: dodecanoyl-[acyl-carrier protein] hydrolase

Comments: acts on the acyl-carrier-protein thioester of C12 and, with a much lower activity, C14 fatty acids. The derivative of oleic acid is hydrolysed very slowly (compare EC 3.1.2.14, oleoyl-[acyl-carrier-protein] hydrolase).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 137903-37-8

References:

1. Pollard, M.R., Anderson, L., Fan, C., Hawkins, D.J., Davies, H.M. A specific acyl-ACP thioesterase implicated in medium-chain fatty acid production in immature cotyledons of Umbellularia californica. Arch. Biochem. Biophys. 284 (1991) 306-312. [PMID: 1989513]

2. Davies, H.M., Anderson, L., Fan, C., Hawkins, D.J. Developmental induction, purification, and further characterization of 12:0-ACP thioesterase from immature cotyledons of Umbellularia californica. Arch. Biochem. Biophys. 290 (1991) 37-45. [PMID: 1898097]

[EC 3.1.2.21 created 1999]


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