IUBMB Enzyme Nomenclature

EC 3.1.13.3

Accepted name: oligonucleotidase

Reaction: Exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates

Other name(s): oligoribonuclease

Comments: Also hydrolyses NAD+ to NMN and AMP. Formerly EC 3.1.4.19.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37288-23-6

References:

1. Futai, M. and Mizuno, D. A new phosphodiesterase forming nucleoside 5'-monophosphate from rat liver. Its partial purification and substrate specificity for nicotinamide adenine dinucleotide and oligonucleotides. J. Biol. Chem. 242 (1967) 5301-5307. [PMID: 4294333]

[EC 3.1.13.3 created 1972 as EC 3.1.4.19, transferred 1978 to EC 3.1.13.3]


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