Reaction: 3'-phosphoadenylyl sulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate
Glossary: 3'-phosphoadenylyl sulfate = PAPS
Other names: steroid alcohol sulfotransferase; 3'-phosphoadenylyl-sulfate:phenolic-steroid sulfotransferase
Systematic name: 3'-phosphoadenylyl-sulfate:phenolic-steroid sulfonotransferase
Comments: Broad specificity resembling EC 2.8.2.2 alcohol sulfotransferase, but also acts on estrone.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9032-76-2
References:
1. Adams, J.B. and McDonald, D. Enzymic synthesis of steroid sulphates. XIII. Isolation and properties of dehydroepiandrosterone sulphotransferase from human foetal adrenals. Biochim. Biophys. Acta 615 (1980) 275-278. [PMID: 6932974]