IUBMB Enzyme Nomenclature

EC 2.7.1.76

Accepted name: 2'-deoxyadenosine kinase

Reaction: ATP + 2'-deoxyadenosine = ADP + dAMP

Other name(s): purine-deoxyribonucleoside kinase

deoxyadenosine kinase (phosphorylating) (ambiguous); purine-deoxyribonucleoside kinase (ambiguous); deoxyadenosine kinase (ambiguous); ATP:deoxyadenosine 5'-phosphotransferase (ambiguous)

Systematic name: ATP:2'-deoxyadenosine 5'-phosphotransferase

Comments: 2'-Deoxyguanosine can also act as acceptor. Possibly identical with EC 2.7.1.74 deoxycytidine kinase.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 37278-12-9

References:

1. Chang, C.H., Brockman, R.W. and Bennett, L.L., Jr. Purification and some properties of a deoxyribonucleoside kinase from L1210 cells. Cancer Res. 42 (1982) 3033-3039. [PMID: 6284353]

2. Krygier, V. and Momparler, R.L. The regulatory properties of deoxyadenosine kinase. Biochim. Biophys. Acta 161 (1968) 578-580. [PMID: 5667299]

[EC 2.7.1.76 created 1972]


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