IUBMB Enzyme Nomenclature

EC 2.7.1.226

Accepted name: L-serine kinase (ADP)

Reaction: ADP + L-serine = AMP + O-phospho-L-serine

Other name(s): serK (gene name)

Systematic name: ADP:L-serine 3-phosphotransferase

Comments: The enzyme, characterized in the hyperthermophilic archaeon Thermococcus kodakarensis, participates in L-cysteine biosynthesis.

Links to other databases: BRENDA, EXPASY, ExplorEnz, KEGG, MetaCyc, CAS registry number:

References:

1. Makino, Y., Sato, T., Kawamura, H., Hachisuka, S.I., Takeno, R., Imanaka, T. and Atomi, H. An archaeal ADP-dependent serine kinase involved in cysteine biosynthesis and serine metabolism. Nat Commun 7 (2016) 13446. [PMID: 27857065]

2. Nagata, R., Fujihashi, M., Kawamura, H., Sato, T., Fujita, T., Atomi, H. and Miki, K. Structural study on the reaction mechanism of a free serine kinase involved in cysteine biosynthesis. ACS Chem. Biol. 12 (2017) 1514-1523. [PMID: 28358477]

[EC 2.7.1.226 created 2019]


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