IUBMB Enzyme Nomenclature

EC 2.7.1.220

Accepted name: D-erythronate 4-kinase

Reaction: ATP + D-erythronate = ADP + 4-phospho-D-erythronate

For diagram of reaction click here

Glossary: D-erythronate = (2R,3R)-2,3,4-trihydroxybutanoate

Other name(s): denK (gene name)

Systematic name: ATP:D-erythronate 4-phosphotransferase

Comments: The enzyme, characterized from bacteria, is involved in a pathway for D-erythronate catabolism.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Zhang, X., Carter, M.S., Vetting, M.W., San Francisco, B., Zhao, S., Al-Obaidi, N.F., Solbiati, J.O., Thiaville, J.J., de Crecy-Lagard, V., Jacobson, M.P., Almo, S.C. and Gerlt, J.A. Assignment of function to a domain of unknown function: DUF1537 is a new kinase family in catabolic pathways for acid sugars. Proc. Natl Acad. Sci. USA 113 (2016) E4161-E4169. [PMID: 27402745]

[EC 2.7.1.220 created 2017]


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