Reaction: CTP + (2E,6E)-farnesol = CDP + (2E,6E)-farnesyl phosphate
For diagram of reaction click here.
Other name(s): FOLK (gene name)
Systematic name: CTP:(2E,6E)-farnesol phosphotransferase
Comments: The enzyme, found in plants and animals, can also use other nucleotide triphosphates as phosphate donor, albeit less efficiently. The plant enzyme can also use geraniol and geranylgeraniol as substrates with lower activity, but not farnesyl phosphate (cf. EC 18.104.22.168, farnesyl phosphate kinase) .
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
1. Bentinger, M., Grunler, J., Peterson, E., Swiezewska, E. and Dallner, G. Phosphorylation of farnesol in rat liver microsomes: properties of farnesol kinase and farnesyl phosphate kinase. Arch. Biochem. Biophys. 353 (1998) 191-198. [PMID: 9606952]
2. Fitzpatrick, A.H., Bhandari, J. and Crowell, D.N. Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis. Plant J. 66 (2011) 1078-1088. [PMID: 21395888]