IUBMB Enzyme Nomenclature

EC 2.7.1.215

Accepted name: erythritol kinase (D-erythritol 1-phosphate-forming)

Reaction: ATP + erythritol = ADP + D-erythritol 1-phosphate

Other name(s): eryA (gene name)

Systematic name: ATP:erythritol 1-phosphotransferase

Comments: The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism. cf. EC 2.7.1.27, erythritol kinase (D-erythritol 4-phosphate-forming).

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Sperry, J.F. and Robertson, D.C. Erythritol catabolism by Brucella abortus. J. Bacteriol. 121 (1975) 619-630. [PMID: 163226]

2. Lillo, A.M., Tetzlaff, C.N., Sangari, F.J. and Cane, D.E. Functional expression and characterization of EryA, the erythritol kinase of Brucella abortus, and enzymatic synthesis of L-erythritol-4-phosphate. Bioorg. Med. Chem. Lett. 13 (2003) 737-739. [PMID: 12639570]

[EC 2.7.1.215 created 2016]


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