Reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate
For diagram click here (mechanism).
Other name(s): 4-hydroxyglutamate aminotransferase
Systematic name: 4-hydroxy-L-glutamate:2-oxoglutarate aminotransferase
Comments: Oxaloacetate can replace 2-oxoglutarate. This enzyme may be identical with EC 188.8.131.52 aspartate transaminase.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37277-86-4
1. Goldstone, A. and Adams, E. Metabolism of γ-hydroxyglutamic acid. I. Conversion to α-hydroxy-γ-ketoglutarate by purified glutamic-aspartic transaminase to rat liver. J. Biol. Chem. 237 (1962) 3476-3485. [PMID: 13948827]
2. Kuratomi, K., Fukunaga, K. and Kobayashi, Y. The metabolism of γ-hydroxyglutamate in rat liver. II. A transaminase concerned in γ-hydroxyglutamate metabolism. Biochim. Biophys. Acta 78 (1963) 629-636.