Reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate
For diagram click here.
Other name(s): O-acetyl-L-homoserine acetate-lyase (adding methanethiol); O-acetyl-L-homoserine sulfhydrolase; O-acetylhomoserine (thiol)-lyase; O-acetylhomoserine sulfhydrolase; methionine synthase (misleading)
Systematic name: O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase
Comments: Also reacts with other thiols and H2S, producing homocysteine or thioethers. The name methionine synthase is more commonly applied to EC 22.214.171.124, methionine synthase. The enzyme from baker's yeast also catalyses the reaction of EC 126.96.36.199 cysteine synthase, but more slowly.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37290-90-7
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