IUBMB Enzyme Nomenclature

EC 2.4.1.342

Accepted name: α-maltose-1-phosphate synthase

Reaction: ADP-α-D-glucose + α-D-glucose-1-phosphate = ADP + α-maltose-1-phosphate

Glossary: maltose = α-D-glucopyranosyl-(1→4)-D-glucose

Other name(s): glgM (gene name)

Systematic name: ADP-α-D-glucose:α-D-glucose-1-phosphate 4-α-D-glucosyltransferase (configuration-retaining)

Comments: The enzyme, found in Mycobacteria, can also use UDP-α-D-glucose with much lower catalytic efficiency.

References:

1. Koliwer-Brandl, H., Syson, K., van de Weerd, R., Chandra, G., Appelmelk, B., Alber, M., Ioerger, T.R., Jacobs, W.R., Jr., Geurtsen, J., Bornemann, S. and Kalscheuer, R. Metabolic network for the biosynthesis of intra- and extracellular α-glucans required for virulence of Mycobacterium tuberculosis. PLoS Pathog. 12 (2016) e1005768. [PMID: 27513637]

[EC 2.4.1.342 created 2016]


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