IUBMB Enzyme Nomenclature

EC 2.3.1.205

Accepted name: fumigaclavine B O-acetyltransferase

Reaction: acetyl-CoA + fumigaclavine B = CoA + fumigaclavine A

For diagram of reaction click here.

Glossary: fumigaclavine B = 6,8β-dimethylergolin-9-ol
fumigaclavine A = 6,8β-dimethylergolin-9β-yl acetate

Other name(s): FgaAT

Systematic name: acetyl-CoA:fumigaclavine B O-acetyltransferase

Comments: The enzyme participates in the biosynthesis of fumigaclavine C, an ergot alkaloid produced by some fungi of the Trichocomaceae family.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Liu, X., Wang, L., Steffan, N., Yin, W.B. and Li, S.M. Ergot alkaloid biosynthesis in Aspergillus fumigatus: FgaAT catalyses the acetylation of fumigaclavine B. ChemBioChem. 10 (2009) 2325-2328. [PMID: 19672909]

[EC 2.3.1.205 created 2012]


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