IUBMB Enzyme Nomenclature


Accepted name: methylmalonyl-CoA carboxytransferase

Reaction: (S)-methylmalonyl-CoA + pyruvate = propanoyl-CoA + oxaloacetate

Other name(s): transcarboxylase; methylmalonyl coenzyme A carboxyltransferase; methylmalonyl-CoA transcarboxylase; oxalacetic transcarboxylase; methylmalonyl-CoA carboxyltransferase; (S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase; (S)-2-methyl-3-oxopropanoyl-CoA:pyruvate carboxyltransferase [incorrect]

Systematic name: (S)-methylmalonyl-CoA:pyruvate carboxytransferase

Comments: A biotinyl-protein, containing cobalt and zinc.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, UM-BBD, CAS registry number: 9029-86-1


1. Hoffmann, A., Hilpert, W. and Dimroth, P. The carboxyltransferase activity of the sodium-ion-translocating methylmalonyl-CoA decarboxylase of Veillonella alcalescens. Eur. J. Biochem. 179 (1989) 645-650. [PMID: 2920730]

2. Swick, R.W. and Wood, H.G. The role of transcarboxylation in propionic acid fermentation. Proc. Natl. Acad. Sci. USA 46 (1960) 28-41.

[EC created 1961]

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