Reaction: 5,10-methylenetetrahydrofolate + D-alanine + H2O = tetrahydrofolate + 2-methylserine
Other name(s): 2-methylserine hydroxymethyltransferase
Systematic name: 5,10-methylenetetrahydrofolate:D-alanine 2-hydroxymethyltransferase
Comments: Also acts on 2-hydroxymethylserine.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, CAS registry number: 9075-76-7
References:
1. Wilson, E.M. and Snell, E.E. Metabolism of α-methylserine. I. α-Methylserine hydroxymethyltransferase. J. Biol. Chem. 237 (1962) 3171-3179.