IUBMB Enzyme Nomenclature


Accepted name: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase

Reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate

Other name(s): transfer ribonucleate 5-methylaminomethyl-2-thiouridylate 5-methyltransferase; tRNA 5-methylaminomethyl-2-thiouridylate 5'-methyltransferase

Systematic name: S-adenosyl-L-methionine:tRNA (5-methylaminomethyl-2-thio-uridylate)-methyltransferase

Comments: This enzyme is specific for the terminal methyl group of 5-methylaminomethyl-2-thiouridylate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 39391-17-8


1. Taya, Y. and Nishimura, S. Biosynthesis of 5-methylaminomethyl-2-thiouridylate. I. Isolation of a new tRNA-methylase specific for 5-methylaminomethyl-2-thiouridylate. Biochem. Biophys. Res. Commun. 51 (1973) 1062-1068. [PMID: 4703553]

2. Taya, Y. and Nishimura, S. In: Salvatore, F., Borek, E., Zappia, V., Williams-Ashman, H.G. and Schlenk, F. (Eds), The Biochemistry of Adenosylmethionine, Columbia University Press, New York, 1977, p. 251.

[EC created 1982, modified 2012]

Return to EC 2.1.1 home page
Return to EC 2.1 home page
Return to EC 2 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page