IUBMB Enzyme Nomenclature

EC 2.1.1.142

Accepted name: cycloartenol 24-C-methyltransferase

Reaction: S-adenosyl-L-methionine + cycloartenol = S-adenosyl-L-homocysteine + (24R)-24-methylcycloart-25-en-3β-ol

For diagram click here.

Other names: sterol C-methyltransferase

Systematic name: S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase

Comments S-Adenosyl-L-methionine methylates the Si face of the 24(25)-double bond with elimination of a hydrogen atom from the pro-Z methyl group at C-25.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 50936-46-4

References:

1. Mangla, A.T. and Nes, W.D. Sterol C-methyl transferase from Prototheca wickerhamii mechanism, sterol specificity and inhibition. Bioorg. Med. Chem. 8 (2000) 925-36. [PMID: 10882005]

[EC 2.1.1.142 created 2001]


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