Reaction: ()-ephedrine + NAD+ = (R)-2-methylimino-1-phenylpropan-1-ol + NADH + H+
Systematic name: ()-ephedrine:NAD+ 2-oxidoreductase
Comments: The product immediately hydrolyses to methylamine and 1-hydroxy-1-phenylpropan-2-one. Acts on a number of related compounds including ()-sympatol, (+)-pseudoephedrine and (+)-norephedrine.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 73508-06-2
1. Klamann, E. and Lingens, F. Degradation of ()-ephedrine by Pseudomonas putida. Detection of ()-ephedrine: NAD+-oxidoreductase from Arthrobacter globiformis. Z. Naturforsch. C: Biosci. 35 (1980) 80-87. [PMID: 7405363]