Reaction: a D-amino acid + H2O + O2 = a 2-oxo carboxylate + NH3 + H2O2
Other name(s): ophio-amino-acid oxidase (ambiguous); L-amino acid:O2 oxidoreductase; new yellow enzyme
Systematic name: D-amino-acid:oxygen oxidoreductase (deaminating)
Comments: A flavoprotein (FAD). Wide specificity for D-amino acids. Also acts on glycine.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9000-88-8
References:
1. Dixon, M. and Kleppe, K. D-Amino acid oxidase. I. Dissociation and recombination of the haloenzyme. Biochim. Biophys. Acta 96 (1965) 357-367.
2. Dixon, M. and Kleppe, K. D-Amino acid oxidase. II. Specificity, competitive inhibition and reaction sequence. Biochim. Biophys. Acta 96 (1965) 368-382.
3. Dixon, M. and Kleppe, K. D-Amino acid oxidase. III. Effect of pH. Biochim. Biophys. Acta 96 (1965) 383-389.
4. Massey, V., Palmer, G. and Bennett, R. The purification and some properties of D-amino acid oxidase. Biochim. Biophys. Acta 48 (1961) 1-9.
5. Meister, A. and Wellner, D. Flavoprotein amino acid oxidase. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd ed., vol. 7, Academic Press, New York, 1963, p. 609-648.