Reaction: L-arginine + H2O + NAD(P)+ = 5-guanidino-2-oxopentanoate + NH3 + NAD(P)H + H+
Other name(s): dauB (gene name); anabolic L-arginine dehydrogenase
Systematic name: L-arginine:NAD(P)+ oxidoreductase (deaminating)
Comments: The enzyme, which has been isolated from the bacterium Pseudomonas aeruginosa PAO1, forms with EC 184.108.40.206, D-arginine dehydrogenase, a two-enzyme complex involved in the racemization of D- and L-arginine.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
1. Li, C. and Lu, C.D. Arginine racemization by coupled catabolic and anabolic dehydrogenases. Proc. Natl. Acad. Sci. USA 106 (2009) 906-911. [PMID: 19139398]