Reaction: an n-alkanal + NADP+ = an alk-2-enal + NADPH + H+
Other name(s): NADPH-dependent alkenal/one oxidoreductase; NADPH:2-alkenal α,β-hydrogenase
Systematic name: n-alkanal:NADP+ 2-oxidoreductase
Comments: Shows highest activity with 1-nitrocyclohexene but also has significant activity with 2-methylpentenal and trans-cinnamaldehyde . Involved in the detoxication of α,β-unsaturated aldehydes and ketones. Has very low activity with NAD as reductant (cf. EC 22.214.171.124, 2-alkenal reductase [NAD(P)+]).
Links to other databases: BRENDA, EXPASY, KEGG Metacyc, CAS registry number:
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