IUBMB Enzyme Nomenclature


Accepted name: cyanocobalamin reductase (cyanide-eliminating)

Reaction: cob(I)alamin + cyanide + NADP+ = cyanocob(III)alamin + NADPH + H+

Other name(s): cyanocobalamin reductase; cyanocobalamin reductase (NADPH, cyanide-eliminating); cyanocobalamin reductase (NADPH; CN-eliminating); NADPH2:cyanocob(III)alamin oxidoreductase (cyanide-eliminating)

Systematic name: cob(I)alamin, cyanide:NADP+ oxidoreductase

Comments: A flavoprotein.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 131145-00-1


1. Watanabe, F., Oki, Y., Nakano, Y. and Kitaoka, S. Occurrence and characterization of cyanocobalamin reductase (NADPH; CN-eliminating) involved in decyanation of cyanocobalamin in Euglena gracilis. J. Nutr. Sci. Vitaminol. 34 (1988) 1-10. [PMID: 3134526]

[EC created 1989 as EC, transferred 2002 to EC]

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